WDR 26 is a new partner of Axin1 in the canonical Wnt signaling pathway
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چکیده
منابع مشابه
WDR26 is a new partner of Axin1 in the canonical Wnt signaling pathway
The stability of β-catenin is very important for canonical Wnt signaling. A protein complex including Axin/APC/GSK3β phosphorylates β-catenin to be degraded by ubiquitination with β-TrCP. In the recent study, we isolated WDR26, a protein that binds to Axin. Here, we found that WDR26 is a negative regulator of the canonical Wnt signaling pathway, and that WDR26 affected β-catenin levels. In addi...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 2016
ISSN: 0014-5793,1873-3468
DOI: 10.1002/1873-3468.12180